"Dr. Stephen McClave is the 34th president of A.S.P.E.N., representing
nearly 6,000 multidisciplinary health care professionals
dedicated to nutrition support therapy. Dr. McClave is a professor
of medicine and the director of clinical nutrition in the Division of
Gastroenterology/Hepatology at the University of Louisville School
of Medicine. He is the author of over 145 articles, book chapters
and medical education tools and was one of the lead authors on the
2009 A.S.P.E.N./SCCM Guidelines for the Provision and Assessment
of Nutrition Support Therapy in the Adult Critically Ill Patient.
His research interests include critical care nutrition, monitoring
patients on early enteral nutrition and aspiration and gastric
residual volumes.
Dr. McClave’s address will focus on current concepts in acute
pancreatitis. The autolysis of the gland and the resultant inflammatory
response generated in severe acute pancreatitis leads to life
threatening oxidative stress. The timing, route, volume and content
of nutrition therapy all impact the degree and duration of stress
and risk from its attendant complications. Novel factors related to
epigenetics and micro-RNA, stimulation of endogenous antioxidant
response element (ARE) and provision of selective antioxidant
micronutrients may allow further modulation of stress to reduce
disease severity and improve outcome."