Gifted teenagers may experience the world in a more intense way than their peers and be incapable of making it perfect as they would wish. Perfectionism is a known risk factor for depression; if combined with overexcitabilities, it may worsen depressive symptoms. This study correlated perfectionism and overexcitabilities with depressive symptoms in gifted adolescents in Paraguay who completed four questionnaires. The results indicated depressive symptoms showed low positive correlations with socially prescribed perfectionism and nondisclosure of imperfection and showed moderate positive correlations with imaginational overexcitability and emotional overexcitability. The study concluded perfectionism and overexcitabilities can moderately predict depressive symptoms.