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Drug Discovery for Diseases of the Developing World
Program Code:
2D
Date:
Tuesday, September 19, 2006
Time:
2:00 PM to 3:45 PM
SPEAKER
(S):
Rashmi Barbhaiya, PhD, Chief Executive Officer & Managing Director, Advinus Therapeutics
Jose F. Garcia-Bustos
Ken Duncan
Robert Don
Ted Sybertz
Lutz Tautz,
Burnham Institute for Medical Research, USA
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Lutz Tautz received his Ph.D. in Organic Chemistry and Biochemistry in 2002 from Karlsruhe University, Germany, under the direction of Professor Janos Retey. He then joined Tomas Mustelin's group at the Burnham Institute for Medical Research La Jolla, CA, where he worked as a postdoctoral associate, and later was promoted to Staff Scientist. He is now a principal investigator at Burnham. His research focuses on key signaling tyrosine phosphatases and their inhibition by small molecules as potential means to treat several types of cancer, including cervical cancer and leukemia, and autoimmune diseases such as type 1 diabetes and rheumatoid arthritis. He applies High Throughput Chemical Library Screening and Structure-Activity-Relationship studies, as well as structure- and ligand-based approaches like Virtual Screening and in silico docking to develop small molecule inhibitors for protein tyrosine phosphatases.
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Chris Hentschel, CEO, Medicines for Malaria Venture
Description
Session Chairs:
Jose F. Garcia-Bustos, GlaxoSmithKline, Spain
Lisa Conte, Napopharma, USA
Pharmaceutical products and vaccines have revolutionized health care in industrialized countries during the last century. However, this progress has barely touched low-income countries where millions of people lack access to essential medicines that could potentially have a remarkable effect on the healthcare of a third of the world's population. Closing the gap between potential and reality entails action in these areas: incentives for academic and industrial R&D in diseases endemic in low-income countries; financing and distribution in resource-constrained areas; drug affordability; effective drug regulation to avoid misuse and fake drugs; and multi-stakeholder community based education, training, and sustainability planning. The panel will explore (a) industry-based solutions to drug development, registration, and distribution in developing and emerging economies; (b) community health initiatives; (c) incentives for tropical disease R&D; and (d) non-profit initiatives to provide access to essential drugs.