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SBS 13th Annual Conference & Exhibition Session List
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SBS 13th Annual Conference & Exhibit Session Recordings


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Package 3 - Online Access – April 17

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Package 4 - Online Access – April 18

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Display sessions grouped by:
Track Session Code Speaker Date

Track: 

2007 Conference Set
 

2007 Conference Set

Complete Conference Set  
Track by Day - April 16th, 2007 
Track by Day - April 17th, 2007  
Track by Day - April 18th, 2007 
Track by Day - April 19th, 2007 
010  Opening Sessions - Keynote: Human Cell Systems Biology for Drug Discovery: Applications to Drug Innovation & Development from Screening to Indication Selection 
020  Keynote : Everyone Depends on Everyone Else 
030  Design and Screening of Synthetic Antibody Libraries (Plenary) 
040  Discovery and Early Development of Antibody Therapeutics 
050  Antibody Fc Engineering for Optimal Immune System Engagement   
060  Immunogenicity Testing for Protein Therapeutics   
070  Differential Targeting of a Protein-Protein Interaction Surface on G-protein Beta/Gamma Subunits (Plenary)   
080  Ubiquitin-Specific Proteases as Novel Cancer Drug Targets: Evaluation of Assay Technologies for High Throughput Screening   
090  High-Throughput Kinetic Analysis of Protein-fragment Interactions Using the Next Generation SPR Slide Imager II for Fragment-based Drug Discovery   
100  NMR Fragment Screening: Successful Case Study on Protein-Protein Interaction Targets   
110  Application of Signal Pathway Mapping to Strategies for Individualized Therapy (Plenary)   
120  Bringing Proteomics to the Clinical Lab: Development of Methods & Bioinformatics   
130  Quantifying Intracellular Signaling Events Using Flow Cytometry Provides a Powerful Tool for Measuring in vivo Target Inhibition for Drug Candidates   
140  A Study of Different Binning Methodologies in NMR-based Metabolomics Analysis   
150  Acoustic Technology: Utilizing Acoustic Technology within GSK: Its Benefits, & Applications for the Future of Compound Management (Plenary)   
160  Creating a Centralized, Flexible, Compound Management Operation   
170  Efficient Sample Logistics: Integrating Support of Lead Optimization & High-Throughput Lead Identification Processes   
180  The Evaluation of the Lead Optimization Phase of Drug Discovery   
190  Preparation of the Plated Compounds forHTS in the Smaller Laboratory   
200  Embryoid Body Cell Migration/Interaction Models: Toward Automatic Cell-by-Cell Tracking (Plenary) 
210  Human Cell Systems as a Broad-based Platform for Drug Discovery: No More Black Box   
220  Use of Human Blood Cells in High-Throughput Screens to Identify Modulators of Cytokine Release   
230  Primary Cells Derived from a Reporter Stem Cell System: A New HTS Tool for Old Targets   
240  Assay Multiplexing with an Imaging Flow Cytometry Platform   
250  The NTP-NCGC-EPA Collaboration on Toxics HTS: Toward a Predictive in vitro Toxicology (Plenary)   
260  PubChem: An Information Resource Linking Chemistry & Biology   
270  Development of EPA's ToxCast Program for Prioritizing the Toxicity Testing of Environmental Chemicals 
280  Data Mining in Toxico-chemical Space: Comparison of Small-molecule Toxicants in Traditional Toxicology Screens, Toxicogenomics & in High-Throughput Toxicity Assays   
290  Toxico-Cheminformatics: Merging Biological & Chemical Information Domains in Support of Toxicity Prediction   
300  Chemical Biology on PINS and NeeDles (Plenary) 
310  Use of Fluorescent Protein FRET Detection in Live Cells: Applications to High-Content Screening 
320  High-throughput Screening Assay Development for Identification of Infectious Disease Inhibitors Using Automated Confocal Microscopy 
330  Screening for Genes: Fluorescence Proteins & Live Cell Screening 
340  Discovery and Validation of Secreted and Transmembrane Proteins as Therapeutic Targets (Plenary)   
350  In Vivo RNAI-Mediated Gene Silencing: Improvements in Systemic Delivery & Efficacy   
360  Genome-wide Drug Target Discovery with siRNA Libraries & Pathway-specific Reporter Vectors 
370  Idenitification of Sensitizers for a Cytostatic Drug Candidate Through an RNA Interference (RNAi) for Modifiers of Drug Action   
380  Promoting Success Rates in the Determination of Protein Structures by the Use of Ligands   
390  Transmembrane Protein Overexpression for Biochemical and Structural Characterization   
400  Structure Based Design of SOD -1 Aggregation Inhibitors: Implications for Development of a New Class ALS Therapeutics   
410  NMR-assisted Discovery of Dishevelled PDZ Domain Inhibitors   
420  High Content Analysis of Phagocytosis Using a Fluorescent Protein from a Reef Coral (Plenary)   
430  Single Cell Insight into the Relationship Between GPCR Expression & Function   
440  Biomarkers for Mitotic Kinase Inhibitor Activities in Tumor Tissue Slices Using High-Content Laser Scanning Cytometry   
450  Multi-Well Based Cell Arrays Enable HCA of Primary Lymphocytes at the Single Cell Resolution   
460  Quantitative Morphological Cytometry for Measuring Shear Stress in Cellular Systems   
470  uSERS -- Label-Free, High-Throughput Screening Platform (Plenary)   
480  Chemical Genomic Tool: Epigenetic Profiling   
490  Modulation of mRNA Stability as a Drug Discovery Platform   
500  Design of a Novel, Cell-based, High-Throughput Screening Assay to Identify Correctors of Protein Trafficking Disruption in Cystic Fibrosis & Initial Results   
510  Online Monitoring of Physiological Parameters of Primary Human Hepatocytes on Silicon Chips   
520  Exploring the Mode of Action of Bioactive Molecules by Chemical-Genetic Profiling in Yeast (Plenary)   
530  Application of Toxicogenomics Towards Drug Safety Evaluation   
540  In Vivo Bioluminescent Detection of Caspase Activation Induced by Anticancer Treatments in Zebrafish Embryos   
550  Predicting Hepatotoxicity for Early Stage Drug Discovery   
560  Genotoxicity Profiling Using HTS & HCS   
570  Phenotypic Fingerprinting of the Cell Cycle & Apoptosis in Cancer Using High-Content Imaging-based Subpopulation Analysis (Plenary)   
580  Targeting Viral Protease-Associated Replication Complexes for Antiviral Chemotherapy: From FRET-based Probes to Novel Antiproteolytic Natural Products   
590  Identification of Direct and Indirect and Inhibitors of Abeta-Induced Calpain Activation in a Cell Model for Alzheimers Disease   
600  Use of High Content Cellular Imaging in Target-directed & Phenotypic Drug Discovery   
610  A Simple & Versatile Assay Platform for Studying Hierarchical Phosphorylation via Micro Parallel Liquid Chromatography 
620  G-protein Coupled Receptor Heterodimerization: Implications for a Role in Signaling & Drug Development   
630  Pharmacological Chaperone-Mediated Rescue of Misfolded Proteins Associated with Genetic Conformational Diseases   
640  The Discovery of Novel Umami Taste Modulators   
650  Screening for Allosteric Modulators of GPCRs   
660  Comparison of Signal-independent Assay Technologies to Second Messenger Assays for Measuring G Protein- Coupled Receptor Pharmacology in a Miniaturized 2ul Ultra High-Throughput Screening Format   
670  Plate-based, Label-free Biosensors not a Panacea, also Indispensible (Plenary)   
680  Potent and Selective Antagonists Validate TRVP3 as a Target for Analgesic Therapeutics   
690  In Vivo Compound Screening in Automated Z-TagSM Zebrafish Cardiotoxicity & Angiogenesis Assays   
700  Targeting Ion Channels in High-throughput Screening   
710  Fragment Screening of Drug Targets by Biophysical Assays & Structural Analysis   
720  Point/CounterPoint Discussion - The NIH Roadmap as a New Model for Drug Discovery: Piplines or Pipedreams   
730  Achievement Awardee Lecture: Beyond the Human Genome Project   
740  Closing Keynote - Molecular Diagnostics: Improved Health & Lower Healthcare Costs   
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