Update on Allogeneic Hematopoietic Cell Transplantation
Program Code: 094580
Wednesday, April 29, 2009
2:00 PM to 3:30 PM (ET)

MODERATOR
Robert Negrin, MD, Director, Divison of Blood and Marrow Transplantation, Stanford Hospital & Clinics

SPEAKERS
Steven Devine, MD, The Ohio State University
Ginna Laport, MD, Stanford University
Krishna Komanduri, M.D., University of Miami Sylvester Cancer Center

DESCRIPTION
The sources of allogeneic hematopoietic cells continues to grow. One speaker will discuss the data supporting the choice of either peripheral blood or marrow as an allogeneic stem cell source as well as alternative cell sources such as cord blood registries and haploidentical donors. With regards to the mobilization of allogeneic hematopoietic cell sources, G-CSF has been the standard for over a decade. But, the advent of newer agents such as the CXCR4 antagonist, AMD3100, may change the standards of both autologous and allogeneic hematopoietic cell collection. Finally, regulatory T cells are a subset of lymphocytes that are increasingly being studied in adoptive immunotherapy protocols. This distinctive T cell population may play a vital role in controlling graft vs host disease in the allogeneic transplant setting.