This audioconference will cover blood transfusion recipient adverse reactions as defined in the National Healthcare Safety Network (NHSN) Biovigilance Component Protocol. Although these definitions were developed by the AABB Hemovigilance Working Group for NHSN participants, they can be used by any transfusion service interested in using standard definitions. The program will apply adverse reaction criteria (definitions) to actual case examples. Some of the reactions that will be discussed include TRALI, TACO, Transfusion Associated Graft vs. Host Disease, hemolytic reactions, allergic reactions and infections.