Peripheral blood and umbilical cord blood have become the most common sources of progenitor cells, however bone marrow harvest, the original source of progenitor cells for clinical use, is once again become a preferred source for a variety of treatments. Both within laboratories and at bedsides, cellular therapy utilizing harvested bone marrow has recently shown to be successful in treatments for tissue repair, immunologic response modification and cellular metabolic function restoration. This session will address issues related to bone marrow harvest technique including safe practices, maintaining personnel competency, and current available equipment. In addition, bone marrow product requirements and characteristics related to novel cellular therapies will be discussed.