Building on the success of prophylactic vaccines that prevent disease against infectious agents, therapeutic vaccines against autoimmune diseases represent an exciting new frontier in immunology research. Therapeutic vaccines hold the potential to address the fundamental immune defect (recognition of self vs non-self) associated with autoimmune disease and promise a new generation of safer, more effective and durable disease-modifying therapeutics. This session will highlight these new technology developments and their application to type 1 diabetes as a case study.

• Highlight current R&D activities, in both academia and biotechnology companies, focused on the development of novel immunotherapeutic vaccines for autoimmune diseases
• Explain mechanism of action of antigen-specific tolerance-inducing therapeutics
• Explain potential clinical application of antigen specific vaccines for autoimmune diseases and commercial potential of immunotherapeutics under development