IMRT II: Clinical and Radiobiology Aspects (Integrating Radiobiology into Planning)
Track
:
EDU
Program Code:
EDU309
Date:
Tuesday, September 23, 2008
Time:
7:15 AM to 8:45 AM
EST
Duration:
4610 Minutes
Location:
253
SPEAKER(S):
Bulent Aydogan, Assistant Professor, University of Chicago
Joseph Deasy, Professor, Washington University School of Medicine
I am currently Professor and Director of the Division of Bioinformatics and Outcomes Research. I have collaborated or directed many studies of radiotherapy dose-volume effects, and their application in treatment planning. I am a member of the QUANTEC (quantitative assessment of normal tissue effects in the clinic) steering committee; QUANTEC and the IJROBP will be publishing a full journal update to dose-volume tolerance reviews this year. I Chair of the Bioinformatics Committee of the RTOG and past Chair of the Biological Effects Committee of the AAPM. I have an ongoing interest in bringing imaging, dosimetric, and biological/biomarker data together into models that predict toxicity risk.
LEARNER OUTCOMES:
Discuss basic factors in tumor and normal tissue dose response (dose-rate; re-oxygenation; acute vs. late response; and the dose-volume effect).
Explain alternative quantitative statements of normal-tissue tolerance, including dose-volume constraints, normal tissue complication probability (NTCP) models, and the generalized equivalent uniform dose.
Explain how the models and data should be used in IMRT treatment planning.