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Session Information

2010 Multidisciplinary Head and Neck Cancer Symposium

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Breakout Session II: Clinical Trial Methodology

Track : Breakout Sessions

Program Code: 11

Date: Friday, February 26, 2010

Time: 1:30 PM to 2:30 PM EST

Duration: 60 Minutes

Location: Akimel 3-4 Ballroom

MODERATOR:

Mitchell Machtay, M.D., University Hospitals Case Medical Center/ Case Western Reserve University

SPEAKER(S):

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Alan Sandler, M.D., Professor, Oregon Health and Science University

Alan Sandler is a Professor of Medicine in the Division of Hematology & Medical Oncology, Department of Medicine, at Oregon Health & Science University in Portland, Oregon where he also serves as the Division Chief of the Hematology & Medical Oncology Division, and is the DeArmond Chair for Clinical Cancer Research. After earning a B.S. in Pharmacy (cum laude) at the University of Toledo in Ohio and an M.D. at Rush Medical College in Chicago, Dr. Sandler completed an internship and residency in Internal Medicine at Yale-New Haven Hospital and a Fellowship in Medical Oncology at the Yale University School of Medicine in New Haven, Connecticut. His academic honors include membership in Alpha Omega Alpha and Rho Chi, the medical and pharmaceutical honor societies. Dr. Sandler is a member of the American Society of Clinical Oncology, and the Eastern Cooperative Oncology Group, where he serves as the Co-Chair of the Thoracic Committee. He is principal investigator or co-principal investigator of several therapeutic clinical trials that evaluate the activity of chemotherapeutic agents and/or combined-modality therapies in both small and non-small cell lung cancer as well as sarcoma. Dr. Sandler serves on the Editorial Boards of Clinical Lung Cancer and the Japanese Journal of Clinical Oncology, and is a reviewer for several journals including The New England Journal of Medicine, Journal of Clinical Oncology, Cancer Investigations, Cancer, the British Journal of Cancer, and European Respiratory Journal. Dr. Sandler is the author or co-author of more than 200 published articles, book chapters, reviews, and abstracts involving the pharmacology and clinical activity of chemotherapy and novel targeted agents, with a particular emphasis on lung cancer.

Arlene Forastiere, M.D., Professor, Johns Hopkins University

J. Jack Lee, Ph.D., M.S., D.D.S., Professor, M.D. Anderson Cancer Center

invited speakers to many conferences to talk on many topics including: "Selecting and Evaluating Efficacy Endpoints for Lung Cancer Trials: What the Investigator and Clinician Should Know About the Statistics," Satellite Symposium on Lung Cancer Efficacy Endpoints, 13th World Conference on Lung Cancer, San Francisco, CA, 8/2/2009 "Adaptive designs based on biomarkers," 13th World Conference on Lung Cancer, San Francisco, CA, 8/4/2009 "Novel Designs in Phase II Studies," AACR Cancer Biostatistics Workshop, Sonoma, CA, 7/14/2009 "Biomarker Based Adaptive Designs for Targeted Agent Development - A Step Toward Personalized Medicine," Biostatistics Workshop in Cancer Research, University of Toronto, Toronto, Canada, 7/25/2009 "Bayesian Adaptive Designs for Targeted Therapy Development for Cancer and Beyond," University of Pennsylvania Annual Conference on Statistical Issues in Clinical Trials: Statistical Issues in Targeted Therapies, Philadelphia, 4/29/2009 "Adaptive designs for speeding up drug discovery," 100th Annual Meeting, American Association for Cancer Research (AACR), Denver, CO, 4/18/2009 Key publications: Xian Zhou DD, Suyu Liu DD, Kim ES, Herbst RS, Lee JJ. Bayesian adaptive design for targeted therapy development in lung cancer--a step toward personalized medicine. Clin Trials 5(3):181-93, 2008. Xian Zhou DD, Suyu Liu DD, Kim ES, Herbst RS, Lee JJ. Bayesian adaptive design for targeted therapy development in lung cancer--a step toward personalized medicine. Clin Trials 5(3):181-93, 2008. Xian Zhou DD, Suyu Liu DD, Kim ES, Herbst RS, Lee JJ. Bayesian adaptive design for targeted therapy development in lung cancer--a step toward personalized medicine. Clin Trials 5(3):181-93, 2008.

Audio Synchronized to PowerPoint

(Code: 11)

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