Many newborns and mothers have increased risk for severe complications of childbirth, including healthcare-associated infections (HAI). Every year more than 4 million babies die in their first 28 days of life; approximately 1/3 of these die of infections acquired during the birth process. The presenters will review several unique health challenges and how infection prevention can improve the health status of women and children in underserved populations.;Objectives: -Review the scope and magnitude of the problem of neonatal and maternal mortality due to complications of childbirth and the role of HAIs -Discuss strategies to reduce potential risk of infection for both babies and mothers