Vaccination of healthcare workers against diseases such as influenza and pertussis, while offering personal protection against these illnesses, may also prevent morbidity and mortality for patients. The presenter will review the recommended vaccinations for healthcare personnel and focus in-depth on influenza and pertussis vaccination. Special attention will be paid to the use of declination statements and mandating influenza vaccination as well as the impact of vaccination on the need for post-exposure prophylaxis for pertussis.;Objectives: • Review the recommended vaccines for healthcare personnel (HCP), including influenza and acellular pertussis vaccines • Develop effective strategies for implementation of vaccines for HCP, including discussion on the use of declinations and mandates for vaccination • Discuss the use of vaccination of HCP as a tool to reduce healthcare-associated infections