The pharmaceutical industry is composed of diverse constituents who, as a whole, result in a unique, overall industry composite. Since the inaugural team of Medical Science Liaisons (MSL) was deployed, the role and function of the individual MSL has evolved and pivoted in numerous directions. Modern day MSLs continue to evolve and represent the crucial link between the academic and investigator community with the pharmaceutical manufacturer. In this symposium, we will explore how an experienced MSL continues to develop professionally; the evolution, innovation, and challenges of the MSL's use of technology in their roles; and the future role of the MSL in educational activities.