Document management systems have been in use by the biotechnology/pharmaceutical industry for decades. Early efforts focused on a central repository approach using first generation technology; this was costly, failure-prone and limited in scope. Sponsors have gained new perspectives through these experiences and intensified efforts to implement advanced content management platforms to increase efficiency, expand and educate new users and address global business / regulatory challenges. This session will explore methods and use cases for how sponsors are revitalizing their content management strategies and platforms to address enterprise needs and how they are gaining new ground and reaping larger benefits.